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Home > Understanding Kidney Disease > Kidney Diseases > Diabetic Nephropathy > Diabetic Nephropathy Basics >

To Avoid Uremia, Diabetics Should Control These Three Indicators Well

2018-07-15 11:42| Font Size A A A

To Avoid Uremia, Diabetics Should Control These Three Indicators Well
Nowadays Diabetic Nephropathy has surpassed glomerulonephritis and become the leading cause of uremia. If you want to avoid uremia, you should control these three indicators, which can help protect your kidneys.

Chronic hyperglycemia will lead to abnormal blood flow throughout the body, damage renal filtration function, impair filtration function, decrease renal detoxification ability, and gradually worsen kidney disease. Eventually you will end in uremia.

To avoid uremia, diabetics should control three indicators, namely blood sugar level, urinary protein and high blood pressure.

1. Blood sugar

For diabetics, the blood glucose target is to control glycosylated hemoglobin below 7%, For middle-aged and elderly patients, this requirement can be relaxed. They can control glycosylated hemoglobin at 7% to 9%.

The choice of hypoglycemic drugs is very important. Many hypoglycemic drugs are excreted by the kidneys. Long-term use will increase the burden on the kidneys. Further aggravation of kidney damage in order to reduce sugar is clearly not worthwhile.

Alpha-glycosidase inhibitors (glucobay, acarbose tablets, and Basen), glinides (NovoNorm, starlix) are relatively friendly to the kidney, and can be used in patients with mild to moderate renal insufficiency.
To Avoid Uremia, Diabetics Should Control These Three Indicators Well

2. Urinary protein

The ideal target of urinary protein is below 0.3g/d. If not, the lowest standard is below 1.0g/d, the lower, the better.

Hormone is commonly used in the clinical practice for proteinuria, but it is not suitable for patients with Diabetic Nephropathy. The antihypertensive drugs such as ACEI and ARBs can be selected to reduce the protein in urine. Although these two drugs are antihypertensive drugs, they have powerful functions, both of which can reduce the protein and protect the kidney. However, if you are diabetic nephropathy patients with renal insufficiency, you had better not use it, because it has a slight effect of elevating creatinine level.
To Avoid Uremia, Diabetics Should Control These Three Indicators Well

3. Control blood pressure

High blood pressure can also do harm to kidneys. It causes a change in hemodynamics, and the kidneys are rich in blood vessels. Constant high blood pressure causes the kidneys to increase the pressure load on the blood vessels, leading to the hardening of kidneys. The ideal target of blood pressure in diabetics is 130/80 mmHg.

The preferred antihypertensive drug is also ACEI or ARBs. If the blood pressure does not decrease to the standard, you can combine these medicines with diuretics, beta receptor blockers and so on to stabilize blood pressure.

Now you know the three indicators that can help diabetics avoid uremia. If you would like to know more information on Diabetic Nephropathy treatment, please leave a message below or send emails to renal-disease@hotmail.com. Renal experts from Beijing Tongshantang Hospital will help you.

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